2293 — memory alpha

Events

Stardate 9522.6: USS Enterprise-A departs the Spacedock One to rendezvous with Kronos One. Captain James T. Kirk is framed for the assassination of Klingon Chancellor Gorkon. He and Dr. Leonard McCoy are given life sentences and sent to the dilithium mines of Rura Penthe but are both rescued by Captain Spock and the crew of the Enterprise-A. (Star Trek VI: The Undiscovered Country)
The USS Enterprise-A is decommissioned. (Star Trek VI: The Undiscovered Country)

Tuvok graduates from Starfleet Academy and is assigned to the starship USS Excelsior, under the command of Captain Sulu. (VOY: "Flashback")
Stardate 9521.6: The Excelsior is struck by a powerful subspace shock wave caused by the destruction of the Klingon moon, Praxis. Upon discovering the cause of the disaster, Sulu immediately contacted the Klingon High Command to offer his ship's assistance. The Klingons, including an officer on Praxis, called for help, however, the transmission was cut off when Brigadier Kerla interrupted and reported that there had been an incident on Praxis, and turned the offer for assistance down because everything is under control, requesting that Sulu obey treaty stipulations and remain outside the Neutral Zone. Thereafter, Sulu reported the incident to Starfleet Command. (Star Trek VI: The Undiscovered Country)

Stardate 9715.5: The USS Enterprise-B is commissioned under the command of Captain John Harriman. (Star Trek Generations, Enterprise-B dedication plaque)
Doing his part to save the Enterprise-B from being destroyed by the Nexus on her maiden voyage, Captain James Tiberius Kirk, one of the most celebrated Starfleet officers in history, is believed to have been killed. (Star Trek Generations)

Stardate 9529.1: The Khitomer Conference takes place, paving the way for nearly a hundred years of peace between the Klingon Empire and the Federation. Curzon Dax is one of the Federation diplomats present who negotiates the Accords. (Star Trek VI: The Undiscovered Country; DS9: "The Way of the Warrior", "You Are Cordially Invited")
The Nexus; a powerful, destructive energy-ribbon and inter-dimensional portal is discovered by the Federation for the first time with the crew of the Enterprise-B. It claims the lives of hundreds of El-Aurian refugees aboard the SS Lakul and SS Robert Fox which were both destroyed by the ribbon. (Star Trek Generations)
Starfleet opens up a classified database on the Borg, likely due to the contact with the El-Aurians, a species that has nearly been wiped out by the Borg, and the mysterious incident in 2153. (VOY: "Scorpion" production art ^{(citation needed • edit)})